By Oriol Güell
This thesis makes use of a systems-level method of examine the mobile metabolism, unveiling new mechanisms and responses that have been most unlikely to arrive with conventional reductionists techniques.
The effects pronounced the following have a possible program in parts like metabolic engineering and disorder therapy. they can even be utilized in deciding upon the accuracy of the gene essentiality of latest genome-scale reconstructions.
Different equipment and methods, in the contexts of structures Biology and the sector often called complicated Networks research were utilized during this paintings to teach assorted positive factors of the robustness of metabolic networks. the categorical matters addressed right here variety from natural topological aspec
ts of the networks themselves to the stability of biochemical fluxes.
Read or Download A Network-Based Approach to Cell Metabolism: From Structure to Flux Balances (Springer Theses) PDF
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