Category Archives: Pharmacology

Functional Hydrogels in Drug Delivery: Key Features and by Umile Gianfranco Spizzirri,Giuseppe Cirillo

| February 24, 2017 | admin | 0

By Umile Gianfranco Spizzirri,Giuseppe Cirillo

The ebook bargains with the synthesis and characterization of hydrogels particularly used as drug supply platforms. every one bankruptcy comprises the latest updates in regards to the diverse beginning fabrics hired and the development in their physicochemical and organic houses to synthetize excessive acting vendors for particular uses.

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Clinical Research Coordinator Handbook: GCP Tools and by Deborah Rosenbaum,Michelle Dresser

| February 24, 2017 | admin | 0

By Deborah Rosenbaum,Michelle Dresser

This revised version of a bestseller presents a logical, step by step advisor to checking out new medications and remedy modalities in compliance with the most recent FDA laws. With present types, ICH GCP details, FDA rules, and different references, it indicates readers tips on how to deal with a scientific examine learn successfully and efficiently.

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Atenção Farmacêutica: Contexto Atual, Exames Laboratoriais e by Paulo Caleb Junior de Lima Santos

| February 24, 2017 | admin | 0

By Paulo Caleb Junior de Lima Santos

Atenção Farmacêutica - Contexto Atual, Exames Laboratoriais e Acompanhmento Farmacoterapêutico insere-se na recomendação da Organização Mundial de Saúde - OMS como prática indispensável na relação paciente-medicamento. O livro tem como público-leitor Farmacêuticos e Graduados em Farmácia orientando-os com muita segurança para o exercício da atenção farmacêutica.

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Biosimilars: A New Generation of Biologics by Jean-Louis Prugnaud,Jean-Hugues Trouvin

| February 24, 2017 | admin | 0

By Jean-Louis Prugnaud,Jean-Hugues Trouvin

Biologics have revolutionised the therapy of many serious stipulations, providing unparalleled scientific effects but in addition generating quite excessive costs. As patents expire, copies and cost pageant are anticipated through the global. although, as a result intrinsic heterogeneity and molecular complexity of biologic medicinal items, their copies can't easily be approved below the “generic rule” legitimate for small chemical entities.

 

In reaction, a devoted legislation was once issued within the ecu Union. it's in accordance with the idea that of “biological medicinal items just like a organic reference product”, or “biosimilars”. This ebook analyses the context of biotechnological construction and addresses the eu felony framework for biosimilar marketplace approval. It highlights post-market authorisation concerns, akin to threat administration Plans and substitution of goods, and descriptions another matters, resembling price administration and overseas nomenclature.

 

This ebook is basically meant for hospital-based physicians and pharmacists. it is going to even be a beneficial source for all actors from all international locations who are looking to higher comprehend the emergence of those new medicinal items in the ecu context.

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Generic Drug Product Development: Solid Oral Dosage Forms: by Leon Shargel

| February 24, 2017 | admin | 0

By Leon Shargel

retaining speed with the most recent applied sciences within the box, this advisor describes the improvement of strong oral general drug items from venture initiation to industry approval. concentrating on immediate-release and modified-release dosage varieties, the ebook collects in-depth discussions from greater than 30 famous experts on subject matters corresponding to qc, experimental formula, pharmaceutical materials, and bioequivalence, and considers key parts within the formula of primary drug items together with the supply of uncooked fabrics, chemical purity. It additionally highlights constraints in frequent drug improvement that fluctuate from the formula layout of a model identify pharmaceutical product.

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Quaaludes (Drugs: the Straight Facts) by Justin T. Gass

| February 24, 2017 | admin | 0

By Justin T. Gass

within the Sixties, methaqualone - bought within the usa because the trademark Quaalude - was once commonly prescribed as a remedy for insomnia and nervousness. notwithstanding, it quickly turned obvious that quaaludes have been hugely addictive and had a robust strength for leisure abuse. in the course of the Nineteen Sixties and '70s, quaaludes have been very hot because of their skill to provide a drunk-like country with no hangover. After years of medical examine printed the damaging brief- and long term results of utilizing quaaludes, the medicine have been made unlawful and pulled from the marketplace in such a lot nations. even if, quaaludes stay abused in lots of constructing countries. "Quaaludes" covers the background of the medication, the actual and mental results, their effect at the mind, their hazards of use and abuse, the portrayal of quaaludes within the media, and coverings for quaalude habit. Chapters of this identify comprise: an outline of Depressant medicinal drugs; What Are Quaaludes?; prior and current Use of Quaaludes; The Neuroscience of Quaalude Use; The actual and mental results of Quaaludes; Quaaludes within the renowned Media; and, difficulties linked to using Quaaludes.

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Karch's Pathology of Drug Abuse, Fourth Edition by Steven B. Karch MD,Olaf Drummer

| February 24, 2017 | admin | 0

By Steven B. Karch MD,Olaf Drummer

Written for practitioners within the box, this seriously acclaimed bestseller presents authoritative info curious about the research of drug-related deaths and sensible techniques to the detection of drug abuse. equipped to supply forensic investigators and pathologists with prepared entry to the authoritative and entire info they wish, Karch’s Pathology of Drug Abuse, Fourth Edition contains—

•          171 new colour photographs and microphotographs

•          forty six tables of comparative details

•          2,000 new references to the literature

Authored by means of a World-Renowned Forensic Pathologist

Steven B. Karch is a fellow in numerous forensic and

toxicological societies and has served a long time as advisor

to either the criminal neighborhood and the pharmaceutical

industry within the usa and the uk.

His bestselling assets are available at the bookshelves

of forensic specialists and pathologists internationally. They

include the vintage Drug Abuse Handbook, and A Brief

History of Cocaine, either of their moment variants, to be had

from CRC Press.

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Arzneitherapie für Ältere (German Edition) by Martin Wehling,Heinrich Burkhardt

| February 24, 2017 | admin | 0

By Martin Wehling,Heinrich Burkhardt

Dieses Buch bietet sichere Arzneitherapie für ältere Patienten und wendet sich mit den folgenden Fragestellungen an die Fachärzte.

  • Welche Besonderheiten es bei älteren Patienten gibt 
  • Welche Nebenwirkungen/Wechselwirkungeninsbesondere beachtet werden müssen und ggfs. als neue eigenständige Erkrankungen fehlinterpretiert werden können
  • Welche Arzneimittel für ältere Patienten ungeeignet sind bzw. besondere Vorsicht erfordern

Menschen im modify über sixty five Jahre bilden die am stärksten wachsende Bevölkerungsgruppe.

Ältere Patienten haben häufig mehrere - oft chronische – Erkrankungen. Unerwünschte Arzneimittelwirkungen sind überdurchschnittlich häufig u.a. wegen:

  • geänderter biologischer Eckdaten (Leberdurchblutung und Nierenfunktion vermindert, mehr Fett- weniger Muskelmasse)
  • mangelnder Compliance
  • Vielfachmedikation mit kaum vorhersagbaren Wechselwirkungen

NEU

Neueste Daten, Statistiken, Key Evidences

Wertungssystem für Alterstauglichkeit von Arzneimitteln nach FORTA-Liste (top-aktuell nach 2. Delphi-Prozess 2015)

Neue Inhalte, u.a.

  • Suchterkrankungen
  • Wechselwirkungen von Medikamenten mit Lebensmitteln (z.B. Grapefruit) oder mit pflanzlichen Arzneimitteln (z.B. Johanniskrautpräparate).

Choosing wisely

Die Lösungsvorschläge und Antworten für die tägliche Praxis:

  • Medizinische Sicherheit: Welche Medikamente haben Priorität? used to be kann/muss ich weglassen?
  • Ökonomische Sicherheit: Bessere Arzneitherapie mit weniger Verschreibungen (= Einhaltung des Arzneimittelbudgets).

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Immune Rebalancing: The Future of Immunosuppression by Diana Boraschi,Giselle Penton-Rol

| February 24, 2017 | admin | 0

By Diana Boraschi,Giselle Penton-Rol

Immune Rebalancing: the way forward for Immunosuppression summarizes the main promising views of immunopharmacology, particularly within the quarter of immunosuppression via contemplating molecular pathways, custom-made drugs, microbiome and nanomedicine.

Modulation of immune responses for healing reasons is a very correct quarter, given the critical position of anomalous immunity in illnesses. those ailments vary from the main generally immune-related syndromes (autoimmune ailments, hypersensitivity and bronchial asthma, immunodeficiencies) to these within which altered immunity and irritation outline the pathological results (chronic infections, tumours, power inflammatory and degenerative illnesses, metabolic issues, etc.

  • Visits immunosuppression from a latest viewpoint of signalling mechanisms on the gentle of the present wisdom of signalling mechanisms and regulatory networks permits the reader to formulate new rules and ideas on the right way to use immunosuppression the healing purposes
  • Encourages researchers to have interaction into exploring the sector of pharmacological modulation of immune responses extensive, and with the recent wisdom and instruments to be had, designs better healing suggestions to autoimmune and inflammatory illnesses, melanoma, degenerative illnesses and infections
  • Examines the hyperlink among molecular pathways linked to immune-suppression and the hot immunopharmacology approaches
  • Provides details at the new concepts for drug improvement during this field
  • Considers the position of microbes within the improvement of the mammalian immune process and immune responses, so as to widen the reader’s procedure for addressing healing immune modulations

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