Electrophysiology of Unconventional Channels and Pores by Anne H. Delcour

By Anne H. Delcour
This ebook is devoted to the channels and pores that belong to an eclectic and ubiquitous type of unconventional - possibly now and then unusual - pore-forming molecules, which however play primary roles in numerous organisms. those non-canonical channels may possibly tackle a number of and occasionally advanced architectures, equivalent to huge beta-barrels or lipid-containing pores. they might originate from micro organism, viruses or intracellular organelles. For a few of them, the physiologically appropriate substrate may perhaps certainly be ions, and for others folded polypeptides. a few are published by means of cells in a soluble shape that has the power to insert into organic membranes to exert its permeabilizing impact. a lot of those unconventional pores were investigated through electrophysiology, which, through its advantage of targeting a couple of or perhaps a unmarried unit, has supplied precious perception into the mechanisms and structure-function relationships of those awesome membrane entities. The chapters of this e-book spotlight a consultant set of those attention-grabbing investigations.
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