By Jan Hermans,Barry Lentz
Progressively builds a deep knowing of macromolecular behavior
Based on all the authors' approximately 40 years of biophysics learn and instructing event, this article instills readers with a deep knowing of the biophysics of macromolecules. It units an outstanding beginning within the fundamentals by way of starting with center actual options akin to thermodynamics, quantum chemical versions, molecular constitution and interactions, and water and the hydrophobic influence. subsequent, the ebook examines statistical mechanics, protein-ligand binding, and conformational balance. ultimately, the authors deal with kinetics and equilibria, exploring underlying thought, protein folding, and stochastic models.
With its robust emphasis on molecular interactions, Equilibria and Kinetics of organic Macromolecules bargains new insights and views on proteins and different macromolecules. The textual content good points insurance of:
- Basic idea, purposes, and new study findings
- Related subject matters in thermodynamics, quantum mechanics, statistical mechanics, and molecular simulations
- Principles and functions of molecular simulations in a committed bankruptcy and interspersed through the text
- Macromolecular binding equilibria from the viewpoint of statistical mechanics
- Stochastic methods relating to macromolecules
Suggested readings on the finish of every bankruptcy comprise unique examine papers, reports and monographs, allowing readers to discover person subject matters in higher intensity. on the finish of the textual content, ten appendices provide refreshers on mathematical remedies, together with likelihood, computational tools, Poisson equations, and defining molecular boundaries.
With its classroom-tested pedagogical strategy, Equilibria and Kinetics of organic Macromolecules is suggested as a graduate-level textbook for biophysics classes and as a reference for researchers who are looking to increase their knowing of macromolecular behavior.
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